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Stages 3 to 4

Chronic Kidney Disease Stages 3 to 4 – Advanced chronic renal insufficiency

  • Physical symptoms. You may still feel completely normal at this stage, or you may begin to experience one or more of the following symptoms:
  • Serum creatinine. Serum creatinine will be higher (indicating less than 30% kidney function)
  • Tiredness or fatigue
  • Puffiness or swelling (obvious in the hands or feet and ankles, but the puffiness will often first be seen around the eyes).
  • Back pain. Chronic kidney disease back pain is usually felt as a dull ache anywhere in the mid-to-lower portion of the back, on one side or the other – this is sometimes referred to as flank pain or loin pain.
  • Appetite. Changes in appetite or eating pattern. Foods may start tasting “funny.”
  • Urine. Changes in urination (amount, color, frequency). Urine may in fact look exceptionally clear at this point, rather than abnormal. This is because little is actually being filtered into it by your kidneys. Previously high proteinuria and/or hematuria may actually improve.
  • Blood pressure. High blood pressure (also referred to as hypertension).
  • Digestion. Poor digestion (varying degrees of gastroparesis, which means that digestion is slowed).

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